Transplant Unit

Publications

Allain J P, Zhai W, Shang D, Lawal Z, Timmers E, Alexander G. HCV hypervariable region diversity and antibody response in relation tocirrhosis. J Med Virol 1999; in press.

Bearcroft P W, Gimson A, Lomas D J. Prospective comparison of a breath hold 2D projection technique with diagnostic ERCP. Radiology (In press).

Bishop N, Ninkovic M, Alexander G, Holmes S, Milligan T, Price C, Compston J. Changes in biochemical markers of bone metabolism in patients undergoing liver transplantation: effects of a single infusion of pamidronate administered pre-operatively. Clinical Science 1999; in press.

Bradley, J, Smith K. Diagnostic tests in Nephrology. Thomson Science London 1998.

Bradley, J, Johnson D, Rubenstein D. Lecture notes on Molecular Medicine. Blackwell Scientific Publications Oxford 2^nd Edition 1999 in press.

Bradley JR and Smith KGC (editors). Diagnostic Tests in Nephrology. Arnold, London, 1999; 297 pages.

Calne RY, Friend PJ, Middleton S, Jamieson NV, Watson CJE, Soin A, Chavez-Cartaya R. Intestinal transplant between two identical triplets. Lancet 350 (1998) 1077-1078.

Calne RY, Friend PJ, Moffat S, Bradley JA, Hale G, Firth JD, Bradley JR, Smith KGC and Waldmann H. Prope Tolerance, perioperative campath 1H and low dose cyclosporin monotherapy in renal allograft recipients. The Lancet 1998;351(9117): 1701-1702.

Calne RY, Moffat S, Friend PJ, Bradley JA, Hale G, Firth JD, Bradley JR,Smith KGC and Waldmann H. Campath 1H allows low dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients. Transplantation 1999; in press.

Caronia S, Taylor K, Pagliaro L, Carr C, Palazzo U, O'Rahilly S, Alexander G. The association between non-insulin dependent diabetes mellitus and chronic hepatitis C virus infection. Hepatology 1999; in press.

Chadban SJ, Bradley JR and Smith KGC. Immunosuppression in Clinical Transplantation in Thiru S and Waldmann H (editors) Pathology and Immunology of Transplantation 1999; In Press.

Cochat P, Jamieson NV, Dubourg L, Gallier JM, Koch Nogueira PC. Combined Liver-kidney Transplantation in Primary Hyperoxaluria Type I. Renal Stone Disease – Crystallization Process, Pathophysiology. Metabolic disorders and Prevention. Edited by Jungers P and Daudon Elsevier M. (1998) 47-52.

Collier JD, Sale J, Friend PJ, Jamieson NV, Calne RY, Alexander G. Graft loss and the antiphospholipid syndrome following liver transplantation. J Hepatology 1998; in press.

Daclizumab Double Therapy Study Group. Reduction of acute renal allograft rejection by Daclizumab. Transplantation 1999; 67: 110-115.

Dyer PA, Taylor CJ, Martin S. HLA and clinical solid organ transplantation: Recent publications and novel approaches (1998). In Eds Gjertson DW, Terasaki PI,. HLA 1998. Pub. American Society for Histocompatibility and Immunogenetics, Lenexa, Kansas, 1998. 13-45.
Dyer P A, Taylor CJ. Renal Transplantation without a pre-transplant crossmatch. Transplantation 1999 (letters) in press.

Evans PC, Gray J, Wreghitt TG, Alexander G. Optimisation of the polymerase chain reaction (PCR) and Dot-Blot hybridisation for detecting cytomegalovirus DNA in urine: comparison with detection of early antigen fluorescent foci (DEAFF) and culture. J Virol Methods 1998; 73: 41-52.

Evans PC, Coleman N, Wreghitt TG, Wight DGD, Alexander G. Cytomegalovirus infection of bile duct epithelial cells, hepatic artery and portal venous endothelium in relation to chronic rejection of liver grafts. J Hepatol 1999: in press.

Evans PC, Gray J, Wreghitt TG, Marcus RE, Alexander G. Comparison of three polymerase chain reaction (PCR) techniques for detecting cytomegalovirus in serum: comparison with detection of early antigen fluorescent foci (DEAFF) and culture. J Med Microbiol 1998; in press.

Evans PC, Soin A, Wreghitt TG, Alexander G. Qualitative and semi-quantitative polymerase chain reaction (PCR) testing for cytomegalovirus DNA in serum allows prediction of CMV-related disease in liver transplant recipients. J Clin Path 1998; 51: 914-921.

Evans PC, Soin A, Wreghitt TG, Taylor C, Wight DGD, Alexander G. Cytomegalovirus infection: A risk factor for chronic rejection after liver transplantation. Transplantation 1999; in press.

Faraco P, Ledgerwood LE and Smith KGC. Apoptosis and acute renal failure. Sepsis 1998:2;31-37.

Feray C, Caccomo L, Alexander G, Ducot B, Gughenheim J, CasanovaT, Loinaz C, Gigou M, Burra P, Barkholt L, Esteban R, Canelo R, Lerut J, Minello-Franza A, Bernard P-H, Nachbaur K, Botta-Fridland D, Maertens G, Bismuth H, Schalm S, Samuel D. European collaborative study on outcome and influential factors following liver transplantation for hepatitis C virus related cirrhosis. Gastroenterology 1999; in press.

Firth JD. Medical treatment of acute tubular necrosis (editorial) QJM 1998;91:321-3.

Griffin SV and Smith KGC. Renal Transplantation. in Bradley JR and Smith KGC (editors). Diagnostic Tests in Nephrology, Arnold, London, 1999; 215-242.

Hirschfield G, Collier JD, Brown R, Taylor C, Frick T, Baglin TP, Alexander G. Donor Factor V Leiden mutation and vascular thrombosis following liver transplantation. Liver Transplantation and Surgery 1998; 4: 58-61.

Hughes J R, Hughes V F, Trull A K, Metcalfe S M. Blood levels of TGFbeta1 in liver transplant recipients receiving either Tacrolimus or microemulsified Cyclosporin.

Hughes VF, Trull AK, Joshi O, Alexander G. Monitoring eosinophil activation and liver function after liver transplantation. Transplantation 1998; 65:1334-1339.

Jacques BC, Ahmiedat H, Gracie JA, Marshall HE, Middleton SE, Bolton EM, Bradley JA. Thymus-dependent, anti-CD4-induced tolerance to rat cardiac allografts. Transplantation 1998; 66: 1291.

Jamieson NV. The Results of combined liver/kidney transplantation for primary hyperoxaluria (PH1) 1984 – 1997. The European PH1 Transplant Registry Report. Journal of Nephrology 11 S-1 (1998) 36 – 41.

Jamieson NV, Victor W. Top tips in Gastrointestinal Surgery. Edited by Ciaran J Walsh. Fazio. Blackwell Science 1999.

Jamieson NV. An overview of abdominal organ preservation for transplantation. In organ Preservation with HTK and UW solution. Update on Clinical Use and experimental studies. Edited by U. J. Hesse and B. De Hemptinnie. Pabst 1999.

Ledgerwood E C, Pober J S, Bradley J R. Recent advances in the molecular basis of TNF signal transduction. Laboratory Investigation. 1999; in press.

MacPhee IAM, Bradley JA, Briggs JD, Junor BR, MacPherson SG, McMillan MA, Rodger SC, Watson MA. Long term outcome of a prospective randomised trial of conversion from Cyclosporin to Azathiaoprine treatment one year after renal transplantation. Transplantation 1998; 66: 1186-1192.

Majid A, Jackson P, Lawal Z, Pearson GMJ, Parker H, Alexander G, Allain J-P Petrik J. Ontogeny of hepatitis C virus (HCV) hypervariable region 1 (HVR1) heterogeneity and anti-HVR1 antibody responses over a three year period in a patient infected with HCV type 2b. J Gen Virol 1999; 80: 317-325.

Martin S and Taylor CJ. The immunologically sensitised renal transplant recipient: the impact of advances in technology on organ allocation and transplant outcome. Transplantation Reviews, 1999; 40-51.

Mason A, Lau J, Hoang N, Qian K, Alexander G, Xu L, Guo L, Chambers R, Jacob S, Regenstein F, Zimmerman R, Everhart J, Wasserfall C, Maclaren N, Perrillo R. Diabetes mellitus and chronic hepatitis C Virus infection. Hepatology 1999; 29: 328-333.

Murphy JM, Maibaum A, Alexander G, Dixon AK. Chiliaditis syndrome and obesity. Human Anatomy 1999; in press.

Newton K, Harris AW, Bath ML, Smith KGC and Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO Journal. 1998; 17: 706-718.

Petrik J, Guella L, Wight DGD, Pearson GM, Hinton J, Parker H, Allain JP, Alexander G. Hepatic histology in hepatitis C virus carriers co-infected with hepatitis G virus. Gut 1998; 42: 103-106.

Pettigrew GJ, Lovegrove E, Bradley JA, Maclean J, Bolton EM. Indirect T cell allorecognition and alloantibody-mediated rejection of MHC class I-disparate heart grafts. Journal of Immunology 1998; 161: 1292.

Richards EM, Alexander G, Nichol J L, Baglin TP. Serum thrombopoeitin levels following liver transplantation. Thrombosis and Haemostasis 1998; 78:1420-1421.

Shepherd R, London M, Alexander G. Enhancing the identification of excessive drinkers on medical wards; a 1-year follow-up study. Alcohol and Alcoholism 1999; 34: 55-58.

Smith KGC and Fearon DT. Receptor modulators of BCR signalling - CD19/22. Current Topics in Microbiology and Immunology 1999;245:195-212.

Smith KGC, Isbel N, Catton M, Becker GJ and Walker RG. Suppression of the humoral immune response to influenza vaccination by mycophenolate mofetil. Nephrology Dialysis Transplantation. 1998; 13(1):160-164.

Smith KGC, Tarlinton DM, Doody GM, Hibbs ML and Fearon DT. Inhibition of the B cell by CD22: a requirement for Lyn. Journal of Experimental Medicine.1998; 187: 807-811.

Smith KGC (editor). Current Opinion in Chronic Rejection. Colwood House, Reading, June 1998.

Smith KGC, Layton J and Tarlinton DM. Antigen specific cells, enrichment and depletion in Roitt, IM and Delves PJ, Encyclopaedia of Immunology (second edition), Academic Press, London, 1998; 178-182.

Taylor CJ, Metcalf Su. Immunobiology of organ transplantation. In Eds Klinck JR, Lindop MJ. Anaesthesia and Intensive Care for Organ Transplantation. Chapman and Hall Medical. London 1998:1-24.

Taylor CJ, Tang KG, Smith SI, White DJ, Davies HF. HLA-specific antibodies in highly sensitised patients can cause a positive crossmatch against pig lymphocytes. Transplantation 1998; 65: 1634-1641.

Taylor CJ, Dyer PA. Maximising the benefits of HLA matching for renal transplantation; alleles, specificities, CREGs, epitopes or residues? Transplantation 1999. In press.

Trull A K. Therapeutic monitoring of Tacrolimus. Ann Clin Biochem 1998;35: 167-80.

Vedi S, Greer S, Huang CC, Garrahan NJ, Ninkovic M, Alexander G, Compston JE. Mechanism of post-transplantation bone disease: early increase in activation frequency and erosion depth. J Bone Mineral Res 1998; in press.

Watson CJE, Friend PJ, Jamieson NV. Sirolimus: A potent new immunosuppressant for Liver Transplantation. Transplantation 1998; 67 (4) 505 – 509.

Wong V, Hughes V, Trull A, Wight DGD, Petrik J, Alexander G. Serum hyaluronic acid is a useful marker of liver fibrosis in chronic hepatitis C virus infection. J Viral Hepatitis 1998; 5: 187-192.

Chapters

Transplantation. Bradley JA.,. In C.V Mann, R.C.G Russell and N.S. Williams eds. Bailey & Love Short Practice of Surgery Arnold: 1999 in press

Clinical Immunosuppresion in renal transplantation. Chadban S., Bradley J R., Smith K G C. In Thiru S and Waldman H ed. Pathology and Immunology of Transplantation Blackwell Science: Oxford 1999 in press

Pathogenesis of jaundice in the critically ill. Gimson A. E. In Oxford Text book of Critical Care Medicine Ed Singer M. Oxford University Press 1998

Diagnosis and management of jaundice in critically ill patients. Gimson A. E. In Oxford Text book of Critical Care Medicine. Ed Singer M. Oxford University Press 1998

Acid – base balance in Fulminant Hepatic Failure. Gimson A. E. In Gullo A (Ed) Anaesthesia, pain, Intensive Care and Emergency Medicine Springer 1998

Endoscopic therapy of Gastro-oesophageal Varices. Gimson A. E. , Collier J In Endoscopic Therapy. Westaby D, Lombard M (Ed) Isis=Medica 1998

Johnson JG., Gore SM., Firth JD., The effect of age, diabetes and other comorbidity on the survival of patients on dialysis; a systematic quantitative overview of the literature. Nephrol Dial (in Press)

Editorials and others

J R Bradley. Family conflicts – the fetal allograft. British Journal of Renal Medicine. 1998; 3 (4): 4

J R Bradley. Buying medicines over the counter. British Journal of Renal Medicine. 1999; 4 (2): 4

Morovat A., Trull A K. Maguire. Serum fructose – 1,6-bisphosphatase for the early detection of acute hepatocellular rejection in liver transplant recipients.